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Statistic
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Details for phenotype: acne vulgaris
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EndoNet ID: ENP00718
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Name
acne vulgaris
General information
This phenotype is not pathologic
Acne vulgaris is a human skin disease, characterized by areas of the skin with seborrhea, comedones, papules, pustules, nodules and possibly scarring.
[1]
Links to other resources
Medline Plus
000873
MeSH term
D000152
Disease database
10765
Phenotype triggers
more activity (high ligand concentration, overexpression) of
AR
ui-button
in
epidermis
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Several experimental observations, therapeutic experience as well as clinical observations support the pathogenic role of androgens in acne. In addition to stimulation of sebum production, indirect evidence also suggests the importance of androgens on comedogenesis and inflammation.
[2]
Reference
