Details for phenotype: vascular smooth muscle cell development

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EndoNet ID: ENP00726

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Name

vascular smooth muscle cell development

General information

This phenotype is not pathologic

Links to other resources

GO	vascular smooth muscle cell development

Phenotype triggers

• normal activity of ER-beta ui-button
  in smooth_muscle ui-button
  • Estradiol is a potent inhibitor of vascular smooth muscle cell growth. [1]
  • Estradiol stimulates cAMP synthesis and cAMP-derived adenosine regulates smooth muscle cell growth via A(2) adenosine receptors. This cAMP-adenosine pathway may contribute to the antivasooclusive effects of estradiol. [1]

EndoNet at the Institut for Bioinformatics UMG Göttingen