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Details for receptor: GRIN1

EndoNet ID: ENR00626

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Synonyms

  • GRIN1
  • glutamate [NMDA] receptor subunit zeta 1
  • N-methyl-D-aspartate receptor subunit NR1

General information

Links to other resources

UniProt Q05586
Ensembl ENST00000371561

Subunit information

long isoform, NR1-3

Sequence
RAACDPKIV NIGAVLSTR KHEQMFREA 
VNQANKRHG SWKIQLNAT SVTHKPNAI 
QMALSVCED LISSQVYAI LVSHPPTPN 
DHFTPTPVS YTAGFYRIP VLGLTTRMS 
IYSDKSIHL SFLRTVPPY SHQSSVWFE 
MMRVYSWNH IILLVSDDH EGRAAQKRL 
ETLLEERES KAEKVLQFD PGTKNVTAL 
LMEAKELEA RVIILSASE DDAATVYRA 
AAMLNMTGS GYVWLVGER EISGNALRY 
APDGILGLQ LINGKNESA HISDAVGVV 
AQAVHELLE KENITDPPR GCVGNTNIW 
KTGPLFKRV LMSSKYADG VTGRVEFNE 
DGDRKFANY SIMNLQNRK LVQVGIYNG 
THVIPNDRK IIWPGGETE KPRGYQMST 
RLKIVTIHQ EPFVYVKPT LSDGTCKEE 
FTVNGDPVK KVICTGPND TSPGSPRHT 
VPQCCYGFC IDLLIKLAR TMNFTYEVH 
LVADGKFGT QERVNNSNK KEWNGMMGE 
LLSGQADMI VAPLTINNE RAQYIEFSK 
PFKYQGLTI LVKKEIPRS TLDSFMQPF 
QSTLWLLVG LSVHVVAVM LYLLDRFSP 
FGRFKVNSE EEEEDALTL SSAMWFSWG 
VLLNSGIGE GAPRSFSAR ILGMVWAGF 
AMIIVASYT ANLAAFLVL DRPEERITG 
INDPRLRNP SDKFIYATV KQSSVDIYF 
RRQVELSTM YRHMEKHNY ESAAEAIQA 
VRDNKLHAF IWDSAVLEF EASQKCDLV 
TTGELFFRS GFGIGMRKD SPWKQNVSL 
SILKSHENG FMEDLDKTW VRYQECDSR 
SNAPATLTF ENMAGVFML VAGGIVAGI 
FLIFIEIAY KRHKDARRK QMQLAFAAV 
NVWRKNLQD RKSGRAEPD PKKKATFRA 
ITSTLASSF KRRRSSKDT STGGGRGAL 
QNQKDTVLP RRAIEREEG QLQLCSRHR 
ES
UniProt Q05586-1

Binding hormones

  • glutamate
  • big dynorphin
    • These results suggest that Big Dyn may efficiently target two systems, the KOR and NMDA (GRIN1-2A-C) receptors. [1]

Anatomical structures with this receptor

    Reference