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Details for receptor: PR B

EndoNet ID: ENR00694

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  • progesterone receptor B
  • NR3C3b
  • PR B

General information

  • PRB was detected in eccrine sweat glands, sebaceous glands, epidermis and outer root sheath of hair follicles. [1]
  • Progesterone receptors A and B differentially modulate corticotropin-releasing hormone. [2]
  • An increase in CRH promoter activity was observed with overexpressed PR-B. [2]

Links to other resources

UniProt P06401-1
Ensembl ENST00000325455

Binding hormones

  • progesterone
    • In vertebrates and humans, the biological activity of progesterone is mediated by two progesterone receptor proteins PR-A and PR-B. [3]

Anatomical structures with this receptor

  • eccrine_sweat_glands

  • sebaceous_glands

    Induced phenotypes

    • sebaceous gland development
      • Progesterone could increase the size of sebaceous glands in spayed rats. [4]
      • But this hormone is not responsible for maintaining sebaceous gland secretion. [5]
  • epidermis

  • hair_follicle