Status
Please wait ...

Details for receptor: prostanoid DP receptor

  • Top
  • General information
  • Subunits
    •
  • External resources
  • General information
  • Hormones
  • Anatomical structures
  • Click to access the toolbox
EndoNet ID: ENR00775

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • DP
  • prostanoid DP receptor
  • prostaglandin D2 receptor
  • PGD receptor
  • DP1

General information

  • DP receptors comediate with CRTH2(chemoattractant receptor-homologous molecule expressed on Th2 cells) the mobilization of eosinophils from bone marrow and their chemotaxis. [1]

Links to other resources

UniProt Q13258
Ensembl ENST00000306051

Subunit information

Sequence 
MKSPFYRCQ NTTSVEKGN SAVMGGVLF 
STGLLGNLL ALGLLARSG LGWCSRRPL 
RPLPSVFYM LVCGLTVTD LLGKCLLSP 
VVLAAYAQN RSLRVLAPA LDNSLCQAF 
AFFMSFFGL SSTLQLLAM ALECWLSLG 
HPFFYRRHI TLRLGALVA PVVSAFSLA 
FCALPFMGF GKFVQYCPG TWCFIQMVH 
EEGSLSVLG YSVLYSSLM ALLVLATVL 
CNLGAMRNL YAMHRRLQR HPRSCTRDC 
AEPRADGRE ASPQPLEEL DHLLLLALM 
TVLFTMCSL PVIYRAYYG AFKDVKEKN 
RTSEEAEDL RALRFLSVI SIVDPWIFI 
IFRSPVFRI FFHKIFIRP LRYRSRCSN 
STNMESSL

Binding hormones

  • PGD2
    • G-protein-coupled receptor [2]
    • stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+ [2]
    • mast cell-derived mediator to trigger asthmatic responses [2]

Anatomical structures with this receptor

    Reference