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Details for receptor: prostanoid DP receptor

EndoNet ID: ENR00775

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Synonyms

  • DP
  • prostanoid DP receptor
  • prostaglandin D2 receptor
  • PGD receptor
  • DP1

General information

  • DP receptors comediate with CRTH2(chemoattractant receptor-homologous molecule expressed on Th2 cells) the mobilization of eosinophils from bone marrow and their chemotaxis. [1]

Links to other resources

UniProt Q13258
Ensembl ENST00000306051

Subunit information

Sequence
MKSPFYRCQ NTTSVEKGN SAVMGGVLF 
STGLLGNLL ALGLLARSG LGWCSRRPL 
RPLPSVFYM LVCGLTVTD LLGKCLLSP 
VVLAAYAQN RSLRVLAPA LDNSLCQAF 
AFFMSFFGL SSTLQLLAM ALECWLSLG 
HPFFYRRHI TLRLGALVA PVVSAFSLA 
FCALPFMGF GKFVQYCPG TWCFIQMVH 
EEGSLSVLG YSVLYSSLM ALLVLATVL 
CNLGAMRNL YAMHRRLQR HPRSCTRDC 
AEPRADGRE ASPQPLEEL DHLLLLALM 
TVLFTMCSL PVIYRAYYG AFKDVKEKN 
RTSEEAEDL RALRFLSVI SIVDPWIFI 
IFRSPVFRI FFHKIFIRP LRYRSRCSN 
STNMESSL

Binding hormones

  • PGD2
    • G-protein-coupled receptor [2]
    • stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+ [2]
    • mast cell-derived mediator to trigger asthmatic responses [2]

Anatomical structures with this receptor

    Reference