Please wait ...

Details for receptor: dopamine receptor D1

EndoNet ID: ENR00784

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be:

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like
If the search pattern is unambigious the user is directed to the corresponding detail page.


  • D1
  • dopamine D1A receptor
  • dopamine receptor D1

General information

  • Stimulatory, acts through G-proteins; activate adenylate cyclase. [1]
  • Both D1(including the D1 and D5)- and D2(including the D2,D3 and D4 receptor)-like receptors have been reported to be expressed in the adrenal medulla, where they modulate catecholamine release. [2]

Links to other resources

UniProt P21728
Ensembl ENST00000393752

Binding hormones

  • dopamine

Anatomical structures with this receptor

  • kidney

  • adrenal_medulla

  • cell_of_adrenal_gland_zona_glomerulosa


    • negative aldosterone
      • Dopmaine has an inhibitory effect on aldosterone secretion. Type 1 dopamine receptor has been demonstrated in the adrenal glomerulosa. [3]
  • hippocampus


    • positive acetylcholine
      • The hippocampal ACh release is facilitated by the local stimulation of D1 receptors. [4]