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Details for receptor: alpha 1D-adrenoreceptor

EndoNet ID: ENR00801

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  • alpha adrenergic receptor 1a (previous)
  • alpha-1D-adrenergic receptor
  • alpha 1D-adrenoreceptor
  • alpha1D-AR
  • alpha-1D adrenergic receptor

General information

  • This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. [1]
  • The cerebellar cortex expresses mRNA encoding all six alpha adrenergic receptor subtypes (1a, 1b, 1d, 2a, 2b, 2c), whereas dentate nucleus neurons express all subtype mRNAs, except alpha2a adrenergic receptor mRNA. [2]

Links to other resources

UniProt P25100
Ensembl ENST00000379453

Binding hormones

    Anatomical structures with this receptor

    • cerebellar_cortex

    • dentate_nucleus

      Induced phenotypes

      • regulation of inhibitory postsynaptic membrane potential
        • Alpha 1D ARs are constitutively active in association with other endogenous recetors to modulate the activity of dentate nucleus neurons. [2]
    • Purkinje_cell