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Details for receptor: galanin receptor 2

EndoNet ID: ENR00928

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Synonyms

  • GalR2
  • galanin receptor 2
  • gal2
  • GALR2
  • GAL2-R

General information

  • Receptor for the hormone galanin and for ; The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via Gq) and that inhibit adenylyl cyclase (via Gi).

Links to other resources

UniProt O43603
Ensembl ENST00000329003

Subunit information

Galanin receptor type 2

Sequence
MNVSGCPGA GNASQAGGG GGWHPEAVI 
VPLLFALIF LVGTVGNTL VLAVLLRGG 
QAVSTTNLF ILNLGVADL CFILCCVPF 
QATIYTLDG WVFGSLLCK AVHFLIFLT 
MHASSFTLA AVSLDRYLA IRYPLHSRE 
LRTPRNALA AIGLIWGLS LLFSGPYLS 
YYRQSQLAN LTVCHPAWS APRRRAMDI 
CTFVFSYLL PVLVLGLTY ARTLRYLWR 
AVDPVAAGS GARRAKRKV TRMILIVAA 
LFCLCWMPH HALILCVWF GQFPLTRAT 
YALRILSHL VSYANSCVN PIVYALVSK 
HFRKGFRTI CAGLLGRAP GRASGRVCA 
AARGTHSGS VLERESSDL LHMSEAAGA 
LRPCPGASQ PCILEPCPG PSWQGPKAG 
DSILTVDVA

Binding hormones

  • galanin
    (trough: blood
    )
    • Cortistatin (CST)... binds all SRIF receptors and also GHS-R. [1]
  • galanin-like peptide Isoform 1

Anatomical structures with this receptor

  • hippocampus

  • kidney

  • central_nerve_system_element

  • paraventricular_nucleus_of_hypothalamus

  • supra-optic_nucleus

Reference