Please wait ...

Details for receptor: THRA1

EndoNet ID: ENR00982

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be:

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like
If the search pattern is unambigious the user is directed to the corresponding detail page.


  • thyroid hormone receptor alpha1
  • THRA1
  • T3R-alpha1
  • NR1A1
  • TRalpha1

General information

  • TRalpha1 mRNA was expressed in the majority (> 90%) of osteoblasts. [1]
  • Expressed in lung. [2]
  • TR-alpha1 mRNA levels in HepG2 are 4-fold higher than in human primary hepatocytes and 5-fold higher than in human liver. [3]

Links to other resources

UniProt P21205
Ensembl ENST00000450525

Binding hormones

  • T3

Anatomical structures with this receptor

  • paraventricular_nucleus_of_hypothalamus


    • negative TRH
  • brain

  • lung

  • chondrocyte

  • osteoblast

  • hepatocyte


    • positive APOA5
      • Treatment with T3 significantly increased APOA5 mRNA levels at 6 h, and a 2-fold induction was achieved after 24 h of T3 addition. [3]
  • macrophage