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Details for receptor: CysLTR2

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EndoNet ID: ENR01052

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http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

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Synonyms

  • CysLTR2
  • cysteinyl leukotriene receptor 2
  • hGPCR21
  • HPN321
  • HG57
  • CYSLT2
  • CYSLT2R

General information

  • Rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4. [1]
  • Highest levels in the heart, placenta, spleen, peripheral blood leukocytes and adrenal gland. Lung (expressed in the interstitial macrophages). Slightly in smooth muscle cells. [1]

Links to other resources

UniProt Q9NS75
Ensembl ENST00000282018

Subunit information

Sequence 
MERKFMSLQ PSISVSEME PNGTFSNNN 
SRNCTIENF KREFFPIVY LIIFFWGVL 
GNGLSIYVF LQPYKKSTS VNVFMLNLA 
ISDLLFIST LPFRADYYL RGSNWIFGD 
LACRIMSYS LYVNMYSSI YFLTVLSVV 
RFLAMVHPF RLLHVTSIR SAWILCGII 
WILIMASSI MLLDSGSEQ NGSVTSCLE 
LNLYKIAKL QTMNYIALV VGCLLPFFT 
LSICYLLII RVLLKVEVP ESGLRVSHR 
KALTTIIIT LIIFFLCFL PYHTLRTVH 
LTTWKVGLC KDRLHKALV ITLALAAAN 
ACFNPLLYY FAGENFKDR LKSALRKGH 
PQKAKTKCV FPVSVWLRK ETRV

Binding hormones

  • LTE4
  • LTC4
  • LTD4

Anatomical structures with this receptor

  • heart

  • placenta

  • spleen

  • peripheral blood leukocytes

  • adrenal_gland

  • lung

  • smooth_muscle

Reference