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Details for receptor: PSGL-1

EndoNet ID: ENR01158

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  • PSGL-1
  • P-selectin glycoprotein ligand 1
  • selectin P ligand
  • CD162 antigen

General information

  • Binds to P-, E- and L-selectins. The calcium-dependent high affinity interaction with P-selectin mediates the tethering and rolling of neutrophils and T-lymphocytes on endothelial cells. [1]
  • PSGL-1 is the primary ligand for P-selectin, and is constitutively expressed on the surface of circulating leukocytes. [2]

Links to other resources

UniProt Q14242
Ensembl ENST00000388962

Binding hormones

  • soluble P-selectin
  • sialoadhesin isoform 2

Anatomical structures with this receptor

  • neutrophil_granulocyte

  • lymphocyte

  • monocyte

  • peripheral blood leukocytes

  • leukocyte