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Details for receptor: ADAM10

EndoNet ID: ENR01198

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  • ADAM10
  • KUZ

General information

  • EGFR ligands sheddase.
  • In the absence of ectodomain shedding, a membrane-anchored ligand (such as TNFalpha or an EGFR ligand) could theoretically only engage a receptor on the same cell (autocrine signalling) or on an immediately adjacent cell (juxtaccrine signalling). [1]

Links to other resources

Binding hormones

  • EGF
  • betacellulin

Anatomical structures with this receptor