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Details for receptor: ephrin-A5

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EndoNet ID: ENR01213

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For an hormone that would be: 

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Synonyms

  • ephrin-A5
  • EFNA5
  • AF1
  • EFL5
  • EPLG7
  • LERK7
  • RAGS
  • eph-related receptor tyrosine kinase ligand 7
  • ephrinA5
  • ephrin A5

General information

  • Ephrin-A5 binds to and activates EphB2 receptor signaling. [1]
  • EphrinA5 and slit2 are important repulsive guidance cues in the developing retinotectal system. [2]
  • Binds to the receptor tyrosine kinases EPHA2, EPHA3 and EPHB1. [3]
  • Eph receptor tyrosine kinases (Ephs) function as molecular relays that interact with cell surface-bound ephrin ligands to direct the position of migrating cells. [4]

Links to other resources

UniProt P52803
Ensembl ENST00000333274

Subunit information

Ephrin-A5.

Sequence 
QDPGSKAVA DRYAVYWNS SNPRFQRGD 
YHIDVCIND YLDVFCPHY EDSVPEDKT 
ERYVLYMVN FDGYSACDH TSKGFKRWE 
CNRPHSPNG PLKFSEKFQ LFTPFSLGF 
EFRPGREYF YISSAIPDN GRRSCLKLK 
VFVRPTNSC MKTIGVHDR VFDVNDKVE 
NSLEPADDT VHESAEPSR GEN
UniProt P52803

Binding hormones

    Anatomical structures with this receptor

    • brain

    Reference