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Details for receptor: GPR39 protein

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EndoNet ID: ENR01312

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

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http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • GPR39 protein
  • GPR39

General information

  • Belongs to the G-protein coupled receptor 1 family.
  • GPR39 is a novel inhibitor of cell death, which might represent a therapeutic target with implications for processes involving apoptosis and endoplasmic reticulum stress like cancer, ischemia/reperfusion injury, and neurodegenerative disease. [1]

Links to other resources

UniProt A4FVA5
Ensembl ENST00000329321

Binding hormones

    Anatomical structures with this receptor

    • hippocampus

      Influences

      • positive pigment epithelium-derived factor
        • GPR39 overexpression leads to increased secretion of the cytoprotective pigment epithelium-dereived growth factor (PEDF). [1]
    Reference