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Details for receptor: IGFBP-5 receptor

EndoNet ID: ENR01313

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  • IGFBP-5 receptor
  • insulin-like growth factor-binding protein 5 receptor

General information

Links to other resources

Binding hormones

    Anatomical structures with this receptor

    • intestinal_smooth_muscle_cell


      • positive IGF-1
        • An IGFBP-5 receptor is present in human intestinal smooth muscle cells. Binding of IGFBP-5 to its cognate receptor activates both the p38 MAP kinase and Erk1/2 signaling cascades. Activation of these pathways by IGFBP-5 mediates jointly stimulation of growth and secretion of IGF-I. [1]