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Details for receptor: Succinate receptor 1

EndoNet ID: ENR01317

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Synonyms

  • Succinate receptor 1
  • G-protein coupled receptor 91
  • P2Y purinoceptor 1-like
  • GPR91

General information

  • Receptor for succinate. [1]
  • GPR91 detected in nephron segments an in the juxtaglomerular apparatus (JGA) [2]
  • Succinate binding to GPR91 has been shown to cause renin release [2]

Links to other resources

UniProt Q9BXA5
Ensembl ENST00000362032

Subunit information

Subunit (1 times)

Sequence
MLGIMAWNA TCKNWLAAE AALEKYYLS 
IFYGIEFVV GVLGNTIVV YGYIFSLKN 
WNSSNIYLF NLSVSDLAF LCTLPMLIR 
SYANGNWIY GDVLCISNR YVLHANLYT 
SILFLTFIS IDRYLIIKY PFREHLLQK 
KEFAILISL AIWVLVTLE LLPILPLIN 
PVITDNGTT CNDFASSGD PNYNLIYSM 
CLTLLGFLI PLFVMCFFY YKIALFLKQ 
RNRQVATAL PLEKPLNLV IMAVVIFSV 
LFTPYHVMR NVRIASRLG SWKQYQCTQ 
VVINSFYIV TRPLAFLNS VINPVFYFL 
LGDHFRDML MNQLRHNFK SLTSFSRWA 
HELLLSFRE K
UniProt Q9BXA5-1

Binding hormones

  • Succinate

Anatomical structures with this receptor

  • kidney

    Influences

    • renin
      • Succinate has been shown to cause renin release from the kidney [2]
  • juxtaglomerular_apparatus

Reference