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Details for messenger / hormone: Dkk4

EndoNet ID: ENH00502

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Synonyms

  • Dkk4
  • Dkk-4
  • dickkopf 4
  • dickkopf-related protein 4
  • hDkk-4
  • DKK4
  • dkk 4

General information

  • Dkk proteins compete for the Lrp5/6 receptor to prevent activation of the canonical signaling pathway. [1]

Classification

Hormone function

  • development and growth
    • embryogenesis

    Chemical classification

    Composition

    Dickkopf homolog 4 short form (mature peptide)

    Sequence 
    SQGRKGQEG ESCLRTFDC GPGLCCARH 
FWTKICKPV LLEGQVCSR RGHKDTAQA 
PEIFQRCDC GPGLLCRSQ LTSNRQHAR 
LRVCQKIEK L

    Links to other resources

    UniProt Q9UBT3
    Ensembl ENST00000220812
    KEGG hsa:27121

      Targets

      Cellkremen 2
      brain Present
      uterus Present
      Reference