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Details for anatomical structure: epithelial cell with microvilli

EndoNet ID: ENC00450

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Synonyms

epithelial cell with microvilli, , Epitheliocytus microvillosus

General information

lines highly absorptive surfaces

Links to other resources

Cytomer cy0011508

Larger structures

  • bronchi
  • skeleton_muscle
  • muscle
  • parts_of_human_body
  • small_intestine
  • digestive_system
  • nasal_mucosa
  • cartilage
  • mucosa_of_small_intestine
  • lung
  • trachea
  • large_intestine

Substructures

    Secreted hormones

    • Hormone: interleukin 6

    • Hormone: HB-EGF

      Influenced by:

      • PAF-R
        in epithelial_cell_with_microvilli

    • Hormone: mucin-2

      Influenced by:

      • EGFR isoform a
        in epithelial_cell_with_microvilli
        • PAFR transduces the signal to EGFR via ADAM10-dependent proteolysis of transmembrane HB-EGF. [1]

    • Hormone: IL-8

      Influenced by:

      • IL-1RI
        in epithelial_cell_with_microvilli
        • IL-1beta and NE (neutrophil elastase) stimulate IL-8 protein production and activate p38 MAPK in bronchial epithelial cells. [2]
      • TNFR1
        in epithelial_cell_with_microvilli

    • Hormone: ICAM-1

      • ICAM-1 expression was up-regulated in a cystic fibrosis cell line. [3]

    • Hormone: BD-1

    • Hormone: ENA-78

    • Hormone: GROalpha

    • Hormone: GRObeta

    • Hormone: GROgamma

    • Hormone: oncostatin M

    • Hormone: GM-CSF

    • Hormone: VEGF-165

    • Hormone: eotaxin-2

    • Hormone: eotaxin-3

    • Hormone: eotaxin

      • Unstimulated cells did not release detectable amounts of CCL11. [4]
      • Cytokine-stimulated alveolar type II epithelial cells express all three eotaxins and possess CCR3 receptors. [4]

      Influenced by:

      • TNFR1
        in epithelial_cell_with_microvilli

    • Hormone: SLPI

      • Expression of the SLPI gene has been extensively examined in superficial epithelial cells from human airways, but SLPI secretion from the superficial epithelium has not yet been clarified [5]
      • SLPI is predominantly in the serous cells of tracheal and bronchial submucosal glands [5]

    • Hormone: fibrinogen

      Influenced by:

      • IL-6R
        in epithelial_cell_with_microvilli
        • We determined the role of IL-6-receptor-gp130-Stat3 signaling in IL-6 activation of the γFBG promoter in liver and lung epithelial cells. [6]

    Receptors

    • Receptor: EGFR isoform a

      Influences:

      • mucin-2
        • PAFR transduces the signal to EGFR via ADAM10-dependent proteolysis of transmembrane HB-EGF. [1]

    • Receptor: PAF-R

      Influences:

      • HB-EGF

    • Receptor: TLR4

    • Receptor: TLR1

    • Receptor: TLR2

    • Receptor: TLR3

    • Receptor: TLR5

    • Receptor: TLR9

    • Receptor: CD14

    • Receptor: IL-1RI

      Influences:

      • IL-8
        • IL-1beta and NE (neutrophil elastase) stimulate IL-8 protein production and activate p38 MAPK in bronchial epithelial cells. [2]

    • Receptor: TLR6

    • Receptor: CCR3

    • Receptor: TNFR1

      Influences:

      • eotaxin
      • IL-8

    • Receptor: IL-4Ralpha

    • Receptor: IL-6R

      Influences:

      • fibrinogen
        • We determined the role of IL-6-receptor-gp130-Stat3 signaling in IL-6 activation of the γFBG promoter in liver and lung epithelial cells. [6]
    Reference